To investigate the status of H. pylori infections this website and its distribution of the chronic gastritis patients. Methods: 300 cases of upper gastrointestinal symptoms, confirmed by endoscopy in patients with chronic gastritis from Sept. to Dec. 2011, the detection of H. pylori was based by the histology of gastric biopsies. Results: Endoscopic diagnosis of chronic non atrophic gastritis (214, 71.3%) was the most common, which confirmed by the pathological diagnosis of chronic non atrophic gastritis was 160, of chronic atrophic gastritis was 54; Endoscopic diagnosis of chronic atrophic gastritis was 86 (28.7%), which confirmed by the pathological

diagnosis Z VAD FMK of chronic atrophic gastritis was 39, of chronic non atrophic gastritis was 47; Pathological diagnosis of the H. pylori positive was103 (34.3%), H. pylori positive of the antrum was 93 (31.0%), the gastric corpus 72 (24.0%); Pathological diagnosis with intestinal metaplasia was 127 (42.3%), IM of the antrum 110, IM of the gastric corpus 41; Intraepithelial neoplasia 86 (28.7%), IEP of the antrum 71, IEP of the gastric corpus 22. Conclusion: The study have shown that current prevalence of chronic atrophic gastritis in Sichuan is high, the Coincidence rate of endoscopic and pathological diagnosis of chronic atrophic gastritis is low. Key Word(s): 1.

Helicobacter pylori; 2. Chronic gastritis; Presenting Author: JI HYUN LEE Additional Authors: SEONG HWAN KIM, SEUNG CHAN

KIM, YOUNG SOOK PARK, YUN JU JO, BYOUNG KWAN SON, SANG BONG AHN, YOUNG KWAN CHO Corresponding Author: JI HYUN LEE, SEONG HWAN KIM Affiliations: Department Mannose-binding protein-associated serine protease of Gastroenterology, Internal Medicine, Eulji University college of Medicine Objective: ESD for gastric neoplasia is currently approved as a standard treatment. After ESD, the use of high dose PPI has been accepted as the treatment of ulcer after ESD. But long term gastric acid suppression provokes into gastric and small intestinal bacterial overgrowth (SIBO) theoretically, there are few reports of SIBO after long term PPIs therapy. So we want to study SIBO after high dose PPIs for post ESD induced ulcer. Methods: The clinical diagnosis of SIBO was made by GBT using lactulose. Total 12 patients who underwent ESD were involved in this study. After 3 months-period of the use of high dose PPI (pantoprozole 20 mg q 12 hours) to these patients, the rate of SIBO positive conversion and affecting factors were investigated. Results: Among 26 patients, 12 patients were excluded by exclusion criteria (use of antibiotics for 3 patients; follow-up refuse of GBT for 7 patients; 2 patients with chronic lung disease). 12 of 14 patientes were negative GBT before high dose PPI use. 4 of 12 patients resulted in GBT positive after high dose PPI.