Four radiologists (two residents without experience in cranial CT and two consultants) independently evaluated all cases. Each radiologist reported findings in 100 patients by using transverse sections only and findings in the other 100 patients by using the unfolded view. The radiologists were blinded to patient names, and patient and group orders were randomized. The results were compared with a standard of reference established by two experts from all prior reading results, all reconstructions, and high-spatial-resolution multiplanar reformats. Logistic regression with repeated measurements
was used for statistical analysis.
Results: The experts found 63 fractures in 30 patients. When transverse sections only were used, the mean patient-based fracture detection rate was 43% (13 of 30) FK506 for inexperienced and 70% (21 of 30) for experienced readers; with curved MIPs, the rates were 80% (24 of 30) and 87% (26 of 30), respectively. Overall sensitivity was higher with curved MIPs (P < .001); specificity was higher with transverse sections (P < .001).
Conclusion: Curved MIPs enable a significantly higher fracture detection
rate than transverse sections. They also considerably close the experience gap in fracture detection rate between residents and experts. (C) RSNA, 2010″
“We report the first observation of ultraviolet superfluorescence (SF) from oxygen vacancies in WO3-x nanowires at room temperature, HDAC inhibitor and of picosecond-scale energy transfer between emission centers (oxygen vacancies) in a plane. A theoretical development from Dicke’s model leads to general formulation for a two-dimensional system, and is applied to explain the energy transfer process. The results demonstrate a possibility to generate ultrafast pulse of ultraviolet light through SF from a localized ensemble of defect states. (C) 2011 American Institute of Physics. [doi:10.1063/1.3514078]“
“Aims: The aim of this analysis is to investigate the mean incremental costs and life expectancy associated with two first-line treatments
for advanced non-squamous non-small cell lung cancer (NSCLC) in Korea and Taiwan; bevacizumab plus cisplatin and gemcitabine (BevCG) and cisplatin plus pemetrexed S3I-201 concentration (CP).
Methods: A health economic (area under curve) model with three health states was developed to assess health outcomes (life-years gained [LYG]), direct costs, and incremental cost-effectiveness ratio (ICER). Progression-free survival (PFS) and overall survival (OS) were derived from randomized clinical trials and used in an indirect comparison in order to estimate their cost effectiveness. A life-time horizon was used. Costs and outcomes were discounted yearly by 5% in Korea and by 3% in Taiwan.
Results: The incremental LYG for the BevCG patients compared with patients treated with CP were 1.10 (13.2 months) in Korea and 1.19 (14.3 months) in Taiwan.